Stochastic fluctuations on the transcriptional stage contribute to isogenic cell-to-cell heterogeneity in mammalian cell populations. Nevertheless, we nonetheless don’t have any clear understanding of the repercussions of this heterogeneity, given the dearth of instruments to independently management imply expression and variability of a gene. Right here, we engineer an artificial circuit to modulate imply expression and heterogeneity of transgenes and endogenous human genes.
The circuit, a Tunable Noise Rheostat (TuNR), consists of a transcriptional cascade of two inducible transcriptional activators, the place the output imply and variance may be modulated by two orthogonal small molecule inputs. On this trend, totally different combos of the inputs can obtain the identical imply however with totally different inhabitants variability.
With TuNR, we obtain low basal expression, over 1000-fold expression of a transgene product, and as much as 7-fold induction of the endogenous gene NGFR. Importantly, for a similar imply expression stage, we’re in a position to set up various levels of heterogeneity in expression inside an isogenic inhabitants, thereby decoupling gene expression noise from its imply. TuNR is subsequently a modular instrument that can be utilized in mammalian cells to allow direct interrogation of the implications of cell-to-cell variability.
Intracellular matrix metalloproteinase-9 mediates epigenetic modifications and autophagy to manage differentiation in human cardiac stem cells
Epigenetic reprogramming and autophagy have crucial roles in differentiation of stem cells. Nevertheless, little or no is thought about how epigenetic modifications are mediated and the way they contribute to autophagy and differentiation in human cardiac stem cells (hCSCs). Beforehand, we’ve got reported that intracellular matrix metalloproteinase-9 (MMP9), a collagenase, mediates cell dying in hCSCs.
Right here, we investigated whether or not intracellular MMP9 mediates epigenetic modifications and autophagy in hCSCs. We created MMP9KO hCSCs and handled them with 5-azacytidine, an inhibitor of DNA methylation, and bafilomycin A1, an inhibitor of autophagosome degradation, and evaluated epigenetic modifications, autophagic flux, and differentiation.
Our outcomes confirmed compromised epigenetic modifications, lowered autophagy, and impaired differentiation in MMP9KO hCSCs. Remarkably, paracrine MMP9 supplementation restored epigenetic modifications however additional lowered autophagy in MMP9KO hCSCs. We conclude that intracellular MMP9 is a crucial mediator of epigenetic modifications and autophagy in hCSCs. Moreover, the endocrine and paracrine results of MMP9 differ for regulating autophagy in hCSCs. These novel roles of MMP9 are precious for stem cell remedy.
Strengthened Poly(ε-caprolactone) Bimodal Foams through Phospho-Calcified Cellulose Nanowhisker for Osteogenic Differentiation of Human Mesenchymal Stem Cells
On this work, phospho-calcified cellulose nanowhiskers (PCCNWs) have been ready from wastepaper powder (WPP) and have been dispersed in poly(ε-caprolactone) (PCL). The biocompatible and biodegradable (PCL)/PCCNW bimodal foam nanocomposites with two species cell sizes have been ready by the solvent casting/particulate leaching methodology in several weight proportion of PCCNWs.
The mechanical, thermal, and in vitro organic properties of PCL/PCCNW nanocomposites have been investigated. All PCL/PCCNW scaffolds have been hydrophilic, biodegradable, and likewise noncytotoxic. The human mesenchymal stem cells have been cultured on the ready PCL/PCCNW bimodal foam nanocomposites and differentiated to osteoblasts.
On the premise of evaluating exams reminiscent of MTT assay, acridine orange/ethidium bromide staining, alkaline phosphatase assay, calcium content material assay, and alizarin purple staining, PCL/PCCNW scaffolds have been launched as an acceptable possibility for emulating the conduct of extracellular matrix. Rising PCCNWs improves the mechanical, hydrophilic, and biodegradability properties of the nanocomposites in addition to their osteoconductivity.
Xanthatin synergizes with cisplatin to suppress homologous recombination by JAK2/STAT4/BARD1 axis in human NSCLC cells
Xanthatin (Xa) is a bicyclic sesquiterpene lactone recognized from the plant Xanthium L. with spectacular antitumor exercise, however the function of Xa in non-small cell lung most cancers (NSCLC) just isn’t recognized. Right here we discovered that Xa inhibits proliferation, migration, invasion and induces apoptosis in NSCLC cells. RNA sequencing and Gene set enrichment evaluation revealed that Xa considerably prompts p53 pathway and suppresses E2F targets, G2M checkpoint and MYC targets in A549 cells.
Amongst these modified genes, the down-regulated gene BARD1 triggered by Xa was recognized as a candidate concerned in Xa’s antitumor impact due to its important function in homologous recombination (HR). Additional research demonstrated that Xa inhibits HR by the BARD1/BRCA1/RAD51 axis, which boosts cell sensitivity to cisplatin. Mechanistic research confirmed that Xa inhibits BARD1 by the JAK2/STAT4 pathway. Our examine revealed that Xa is a promising drug to deal with NSCLC, particularly together with typical chemotherapy.
Evaluation of Picture-Induced Cytotoxic Exercise of Cachrys sicula and Cachrys libanotis Enriched-Coumarin Extracts towards Human Melanoma Cells
Photochemotherapy is without doubt one of the most attention-grabbing present therapeutic approaches for the therapy of melanoma. Totally different courses of naturally occurring phytochemicals demonstrated attention-grabbing photoactive properties. The intention of this examine was to judge the photocytotoxic potential of two Cachrys species from Southern Italy: C. sicula and C. libanotis (Apiaceae).
The enriched-coumarin extracts have been obtained from aerial elements by each conventional maceration and pressurized cyclic solid-liquid (PCSL) extraction utilizing Naviglio extractor®. Qualitative and quantitative analyses of furanocoumarins have been carried out with GC-MS. The photocytotoxic results have been verified on C32 melanoma cells irradiated at a dose of 1.08 J/cm2.
The apoptotic responses have been additionally assessed. Furthermore, phenolic content material and the in vitro antioxidant potential have been estimated. Xanthotoxin, bergapten, and isopimpinellin have been recognized. All of the samples induced concentration-dependent photocytotoxic results (IC50 starting from 3.16 to 18.18 μg/mL). The C. libanotis pattern obtained with Naviglio extractor® was the simplest one (IC50 = 3.16 ± 0.21 μg/mL), adopted by C. sicula pattern obtained with the identical method (IC50 = 8.83 ± 0.20 μg/mL). Each Cachrys samples obtained by PCSL induced up-regulation of apoptotic alerts reminiscent of BAX (Bcl2-associated X protein) and PARP (poly ADP-ribose polymerase) cleavage.
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNC401506-500 | Biotium | 500uL | EUR 652.8 |
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Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF640R conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
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| BNC401888-100 | Biotium | 100uL | EUR 279.6 |
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Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF640R conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC401888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF640R conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC551506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF555 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC551506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF555 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNC051506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF405M conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC051506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF405M conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC051888-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF405M conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC051888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF405M conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNC471506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF647 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC471506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF647 conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC471888-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF647 conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC471888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF647 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC801506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF680 conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC801506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF680 conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC801888-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF680 conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC801888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF680 conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNC811506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF680R conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC811506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF680R conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNC611506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF660R conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC611506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF660R conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC611888-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF660R conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC611888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF660R conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC551888-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF555 conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC551888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF555 conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
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| BNUB1888-100 | Biotium | 100uL | EUR 316.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Concentration: 0.2mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
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| BNUB1888-50 | Biotium | 50uL | EUR 486 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), 1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
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| BNUB1888-500 | Biotium | 500uL | EUR 615.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Concentration: 0.2mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNUM1506-50 | Biotium | 50uL | EUR 474 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNCB1506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),Biotin conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNCB1506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),Biotin conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNCB1888-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNCB1888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNCH1506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNCH1506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNCH1888-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNCH1888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNCP1506-250 | Biotium | 250uL | EUR 459.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),PerCP conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNC941506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF594 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC941506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF594 conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC941888-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF594 conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC941888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF594 conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNCAP1506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNCAP1506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNCAP1888-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNCAP1888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNCA1506-250 | Biotium | 250uL | EUR 459.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),APC conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNCA1888-250 | Biotium | 250uL | EUR 472.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), APC conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC881888-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF488A conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC881888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF488A conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNUB1506-100 | Biotium | 100uL | EUR 250.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), Concentration: 0.2mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNUB1506-500 | Biotium | 500uL | EUR 549.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), Concentration: 0.2mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC041506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF405S conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC041506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF405S conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC041888-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF405S conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
|||
| BNC041888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF405S conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC881506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF488A conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC881506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF488A conjugate, Concentration: 0.1mg/mL |
|||
CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
|||
| BNC701506-100 | Biotium | 100uL | EUR 238.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF770 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNC701506-500 | Biotium | 500uL | EUR 652.8 |
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Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF770 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
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| BNC701888-100 | Biotium | 100uL | EUR 279.6 |
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Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF770 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
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| BNC701888-500 | Biotium | 500uL | EUR 654 |
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Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF770 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNC681506-100 | Biotium | 100uL | EUR 238.8 |
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Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF568 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNC681506-500 | Biotium | 500uL | EUR 652.8 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),CF568 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
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| BNC811888-100 | Biotium | 100uL | EUR 279.6 |
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Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF680R conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
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| BNC811888-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF680R conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
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| BNC681888-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF568 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
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| BNC681888-500 | Biotium | 500uL | EUR 654 |
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Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), CF568 conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
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| BNCP1888-250 | Biotium | 250uL | EUR 472.8 |
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Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), PerCP conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R) Antibody |
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| BNCR1506-250 | Biotium | 250uL | EUR 459.6 |
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Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R),RPE conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711) Antibody |
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| BNCR1888-250 | Biotium | 250uL | EUR 472.8 |
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Description: Primary antibody against CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), RPE conjugate, Concentration: 0.1mg/mL |
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CD1a / HTA1 (Mature Langerhans Cells Marker); Clone O10 (Concentrate) |
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| RA0031-C.1 | ScyTek Laboratories | 0.1 ml | EUR 150 |
CD1a / HTA1 (Mature Langerhans Cells Marker); Clone O10 (Concentrate) |
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| RA0031-C.5 | ScyTek Laboratories | 0.5 ml | EUR 360 |
CD1a / HTA1 (Mature Langerhans Cells Marker); Clone C1A/711 (Concentrate) |
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| RA0032-C.1 | ScyTek Laboratories | 0.1 ml | EUR 150 |
CD1a / HTA1 (Mature Langerhans Cells Marker); Clone C1A/711 (Concentrate) |
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| RA0032-C.5 | ScyTek Laboratories | 0.5 ml | EUR 360 |
Anti-CD1a / HTA1 (Mature Langerhans Cells Marker) Monoclonal Antibody |
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| M00375 | BosterBio | 100ug/vial | EUR 476.4 |
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Description: Mouse Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody. Validated in IHC and tested in Human. |
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Monoclonal CD1a (Mature Langerhans Cells Marker) Antibody, Clone: SPM120 |
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| AMM01440G | Leading Biology | 7 ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human CD1a (Mature Langerhans Cells Marker). The antibodies are raised in Mouse and are from clone SPM120. This antibody is applicable in IHC, IF, FC |
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CD1a / HTA1 (Mature Langerhans Cells Marker); Clone O10 & C1A/711 (Concentrate) |
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| RA0033-C.1 | ScyTek Laboratories | 0.1 ml | EUR 150 |
CD1a / HTA1 (Mature Langerhans Cells Marker); Clone O10 & C1A/711 (Concentrate) |
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| RA0033-C.5 | ScyTek Laboratories | 0.5 ml | EUR 360 |
Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody, Clone: O10 |
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| AMM01439G | Leading Biology | 7 ml | EUR 580.8 |
|
Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker). The antibodies are raised in Mouse and are from clone O10. This antibody is applicable in IHC, IF, FC |
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Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody, Clone: C1A/711 |
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| AMM01441G | Leading Biology | 7 ml | EUR 580.8 |
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Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker). The antibodies are raised in Mouse and are from clone C1A/711. This antibody is applicable in IHC, IF, FC |
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Mouse Anti Guinea Pig Lymphocytes And Langerhans Cells Monoclonal Antibody |
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| DMABT-51929MG | Creative Diagnostics | 2 ml | EUR 889.2 |
Islets of Langerhans, Peptide Aptamer, unlabeled |
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| AP-317-U | Alpha Diagnostics | 5 mg | Ask for price |
Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody, Clone: O10 + C1A/711 |
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| AMM01442G | Leading Biology | 7 ml | EUR 580.8 |
|
Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker). The antibodies are raised in Mouse and are from clone O10 + C1A/711. This antibody is applicable in IHC, IF, FC |
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Islets of Langerhans, Peptide Aptamer, Biotinylated |
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| AP-317-B | Alpha Diagnostics | 1 mg | Ask for price |
Islets of Langerhans, Peptide Aptamer, FITC labelled |
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| AP-317-F | Alpha Diagnostics | 1 mg | Ask for price |
Monoclonal CD1a (Mature Langerhans Cells Marker) Antibody - With BSA and Azide, Clone: SPM120 |
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| AMM00439G | Leading Biology | 0.05mg | EUR 475.2 |
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Description: A Monoclonal antibody against Human CD1a (Mature Langerhans Cells Marker) - With BSA and Azide. The antibodies are raised in Mouse and are from clone SPM120. This antibody is applicable in IHC-P, IF, FC |
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Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - With BSA and Azide, Clone: O10 |
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| AMM00172G | Leading Biology | 0.05mg | EUR 475.2 |
|
Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker) - With BSA and Azide. The antibodies are raised in Mouse and are from clone O10. This antibody is applicable in WB, IHC and IF, FC, IP, E |
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Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - With BSA and Azide, Clone: CBT6 |
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| AMM01445G | Leading Biology | 0.05mg | EUR 475.2 |
|
Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker) - With BSA and Azide. The antibodies are raised in Mouse and are from clone CBT6. This antibody is applicable in IF, FC |
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Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - With BSA and Azide, Clone: C1A/711 |
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| AMM00073G | Leading Biology | 0.05mg | EUR 475.2 |
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Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker) - With BSA and Azide. The antibodies are raised in Mouse and are from clone C1A/711. This antibody is applicable in WB, IHC and IF, FC, IP, E |
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Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - Without BSA and Azide, Clone: O10 |
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| AMM00438G | Leading Biology | 0.1mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker) - Without BSA and Azide. The antibodies are raised in Mouse and are from clone O10. This antibody is applicable in IHC-P, IF, FC |
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Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - With BSA and Azide, Clone: 66IIC7 |
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| AMM01443G | Leading Biology | 0.05mg | EUR 475.2 |
|
Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker) - With BSA and Azide. The antibodies are raised in Mouse and are from clone 66IIC7. This antibody is applicable in IHC, IF, FC |
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Monoclonal CD1a (Mature Langerhans Cells Marker) Antibody - Without BSA and Azide, Clone: SPM120 |
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| AMM00440G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human CD1a (Mature Langerhans Cells Marker) - Without BSA and Azide. The antibodies are raised in Mouse and are from clone SPM120. This antibody is applicable in IHC-P, IF, FC |
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Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - With BSA and Azide, Clone: O10+C1A/711 |
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| AMM00173G | Leading Biology | 0.05mg | EUR 475.2 |
|
Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker) - With BSA and Azide. The antibodies are raised in Mouse and are from clone O10+C1A/711. This antibody is applicable in WB, IHC and IF, FC, IP |
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Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - Without BSA and Azide, Clone: C1A/711 |
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| AMM00441G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker) - Without BSA and Azide. The antibodies are raised in Mouse and are from clone C1A/711. This antibody is applicable in IHC-P, IF, FC |
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Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - Without BSA and Azide, Clone: CBT6 |
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| AMM01446G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker) - Without BSA and Azide. The antibodies are raised in Mouse and are from clone CBT6. This antibody is applicable in IF, FC |
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Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - Without BSA and Azide, Clone: 66IIC7 |
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| AMM01444G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker) - Without BSA and Azide. The antibodies are raised in Mouse and are from clone 66IIC7. This antibody is applicable in IHC, IF, FC |
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Monoclonal CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody - Without BSA and Azide, Clone: O10 + C1A/711 |
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| AMM00442G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human CD1a / HTA1 (Mature Langerhans Cells Marker) - Without BSA and Azide. The antibodies are raised in Mouse and are from clone O10 + C1A/711. This antibody is applicable in IHC-P, IF, FC |
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293AD Cell Line |
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| AD-100 | Cell Biolabs | 1 vial | EUR 553.2 |
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Description: The 293AD Cell Line is derived from the parental 293 cells but selected for attributes that increase adenovirus production, including firmer attachment and larger surface area. |
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293AAV Cell Line |
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| AAV-100 | Cell Biolabs | 1 vial | EUR 609.6 |
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Description: The 293AAV Cell Line is derived from the parental 293 cells but selected for attributes that increase AAV production, including firmer attachment and larger surface area. |
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293LTV Cell Line |
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| LTV-100 | Cell Biolabs | 1 vial | EUR 609.6 |
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Description: The 293LTV Cell Line is derived from the parental 293 cells but selected for attributes that increase lentiviral production, including fimrer attachment and larger surface area. |
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293RTV Cell Line |
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| RV-100 | Cell Biolabs | 1 vial | EUR 609.6 |
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Description: The 293RTV Cell Line is derived from the parental 293 cells but selected for attributes that increase retroviral production, including fimrer attachment and larger surface area. |
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CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric |
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| CBA-135 | Cell Biolabs | 96 assays | EUR 985.2 |
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Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
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CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric |
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| CBA-135-5 | Cell Biolabs | 5 x 96 assays | EUR 4027.2 |
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Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
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CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Fluorometric |
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| CBA-140 | Cell Biolabs | 96 assays | EUR 1027.2 |
|
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
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CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Fluorometric |
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| CBA-140-5 | Cell Biolabs | 5 x 96 assays | EUR 4179.6 |
|
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
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StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible) |
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| CBA-325 | Cell Biolabs | 96 assays | EUR 1027.2 |
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Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis. |
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StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible) |
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| CBA-325-5 | Cell Biolabs | 5 x 96 assays | EUR 4033.2 |
|
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis. |
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293/GFP Cell Line |
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| AKR-200 | Cell Biolabs | 1 vial | EUR 686.4 |
|
Description: 293/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
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T47D/GFP Cell Line |
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| AKR-208 | Cell Biolabs | 1 vial | EUR 686.4 |
|
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
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A549/GFP Cell Line |
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| AKR-209 | Cell Biolabs | 1 vial | EUR 686.4 |
|
Description: A549/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
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HeLa/GFP Cell Line |
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| AKR-213 | Cell Biolabs | 1 vial | EUR 686.4 |
|
Description: HeLa/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
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293/Cas9 Cell Line |
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| AKR-5110 | Cell Biolabs | 1 vial | EUR 686.4 |
HeLa/Cas9 Cell Line |
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| AKR-5111 | Cell Biolabs | 1 vial | EUR 686.4 |
NIH3T3/GFP Cell Line |
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| AKR-214 | Cell Biolabs | 1 vial | EUR 686.4 |
|
Description: NIH3T3/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
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NIH3T3/Cas9 Cell Line |
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| AKR-5104 | Cell Biolabs | 1 vial | EUR 686.4 |
CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric, Trial Size |
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| CBA-135-T | Cell Biolabs | 24 assays | EUR 518.4 |
|
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
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MCF-7/Luc Cell Line |
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| AKR-234 | Cell Biolabs | 1 vial | EUR 686.4 |
|
Description: MCF-7/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line. |
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SKOV-3/Luc Cell Line |
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| AKR-232 | Cell Biolabs | 1 vial | EUR 686.4 |
|
Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line. |
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OVCAR-5/RFP Cell Line |
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| AKR-254 | Cell Biolabs | 1 vial | EUR 686.4 |
|
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line. |
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CytoSelect 96-Well Cell Transformation Assay (Cell Recovery Compatible, Fluorometric), Trial Size |
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| CBA-140-T | Cell Biolabs | 24 assays | EUR 547.2 |
|
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
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Furthermore, these samples proved to be extra photoactive, giving a better upregulation of p21 protein within the presence of UVA radiation. Obtained outcomes recommend that investigated species could possibly be promising candidates for additional investigations aimed to search out new potential medicine for the photochemotherapy of pores and skin most cancers.