Libertellenone H (LH), a marine-derived pimarane diterpenoid remoted from arctic fungus Eutypella sp. D-1, has proven efficient cytotoxicity on a variety of most cancers cells. The current research is to discover the anticancer impact of LH on human pancreatic most cancers cells and to research the intracellular molecular goal and underlying mechanism. As proven, LH exhibited anticancer exercise in human pancreatic most cancers cells by selling cell apoptosis.
Mechanistic research steered that LH-induced reactive oxygen species (ROS) accumulation was chargeable for apoptosis as antioxidant N-acetylcysteine (NAC) and antioxidant enzyme superoxide dismutase (SOD) antagonized the inhibitory impact of LH. Zymologic testing demonstrated that LH inhibited Trx system however had little impact on the glutathione reductase and glutaredoxin.
Mass spectrometry (MS) evaluation revealed that the mechanism of motion was primarily based on the direct conjugation of LH to the Cys32/Cys35 residue of Trx1 and Sec498 of TrxR, resulting in a lower within the mobile stage of glutathione (GSH) and activation of downstream ASK1/JNK signaling pathway. Taken collectively, our findings revealed LH was a marine derived inhibitor of Trx system and an anticancer candidate.
Human endogenous retrovirus W household envelope protein (HERV-W env) facilitates the manufacturing of TNF-α and IL-10 by inhibiting MyD88s in glial cells
Human endogenous retrovirus W household envelope protein (HERV-W env) is related to a number of neurological and psychiatric problems, together with a number of sclerosis (MS) and schizophrenia. Medical research have demonstrated a typical hyperlink between inflammatory abnormalities and HERV-W env in neuropsychiatric ailments. Nonetheless, the molecular mechanisms by which HERV-W env mediates neuroinflammation are nonetheless unclear. On this research, we discovered that HERV-W env considerably elevated the mRNA and protein ranges of TNF-α and IL-10 in U251 and A172 cells. HERV-W env additionally induced a notable enhance in Toll-like receptor 4 (TLR4).
Knockdown of TLR4 impaired the expressions of TNF-α and IL-10 induced by HERV-W env. Overexpression of HERV-W env led to the upregulation of MyD88 however prompted a lower in MyD88s. MyD88s overexpression suppressed the expressions of TNF-α and IL-10 induced by HERV-W env. These findings point out that HERV-W env upregulates the expressions of IL-10 and TNF-α by inhibiting the manufacturing of MyD88s in glial cells. This work sheds gentle on the immune pathogenesis of HERV-W env in neuropsychiatric problems.
Single cell ATAC-Seq reveals cell type-specific transcriptional regulation and distinctive chromatin accessibility in human spermatogenesis
Throughout human spermatogenesis, germ cells endure dynamic adjustments in chromatin group/re-packaging and in transcriptomes. To be able to higher perceive the underlying mechanism(s), scATAC-Seq of 5376 testicular cells from three regular males have been carried out. Knowledge have been analyzed in parallel with the scRNA-Seq knowledge of human testicular cells. Ten germ cell varieties related to spermatogenesis and 6 testicular somatic cell varieties have been recognized, together with 142 024 peaks situated in promoter, genebody and CpG Island.
We had examined chromatin accessibility of all chromosomes, with chromosomes 19 and 17 emerged because the main chromosomes that displayed excessive chromatin accessibility. In accessible chromatin areas, transcription issue (TF)-binding websites have been recognized and particular motifs with excessive frequencies at completely different spermatogenesis phases have been detected, together with CTCF, BORIS, NFY, DMRT6, EN1, ISL1 and GLI3.
Two most notable observations have been famous. First, TLE3 was particularly expressed in differentiating spermatogonia. Second, PFN4 was discovered to be concerned in actin cytoskeletal group throughout meiosis. Extra vital, distinctive areas upstream of PFN4 and TLE3 have been proven to show excessive accessibility, illustrating their significance in supporting human spermatogenesis.
Novel copolymers drive differentiation of human adipose derived stem cells in direction of chondrocytes and osteoblasts recognized by high-throughput strategy
Human adipose derived stem cells (hASCs) have been seeded onto polymer microarrays that had been fabricated utilizing quite a lot of acrylate monomers to find novel substrates that induced differentiation in direction of chondrocytes and osteoblasts. Circulate cytometric evaluation confirmed that each CD105 and CD49d optimistic hASCs elevated quickly with passage quantity on the lead polymers, whereas quantitative PCR evaluation confirmed that the substrate synthesized from methacryloxyethyltrimethyl ammonium chloride, N,N-diethylaminoethyl methacrylate and cyclohexyl methacrylate enhanced chondrogenesis and osteogenensis some Four and 25 occasions respectively when it comes to the expression of SOX9 and ALP in differentiated stem cells. These copolymers substrates thus have nice potential for software within the purification, era and growth of outlined hASC’s and the managed differentiation of of cells for attainable medical software.
Osteogenic differentiation capacity of human mesenchymal stem cells on Chitosan/Poly (Caprolactone)/nano beta Tricalcium Phosphate composite scaffolds
Our work depicts the event and characterization of Chitosan/Poly (caprolactone)/nano beta-Tricalcium phosphate (CS/PCL/β-TCP) porous composite scaffolds by freeze drying methodology. Addition of PCL to CS/β-TCP composite scaffolds had considerably elevated the compressive power apart from decelerating the degradation fee. Human mesenchymal stem cells (hMSCs) have been chosen to evaluate in-vitro biocompatibility of the ready scaffolds when it comes to cell viability, cell attachment and proliferation by MTT assay, SEM and DNA Quantification assays respectively.
 Anti-Human Betacellulin Antibody |
|
101-M230 |
ReliaTech |
100 µg |
EUR 399 |
|
Description: Betacellulin (BTC) is a new member of the EGF family of cytokines that is comprised of at least ten proteins including EGF, TGF αlpha, amphiregulin, HBEGF, and the various heregulins. All of these cytokines are synthesized as transmembrane precursors and are characterized by the presence of one or more EGF structural units in their extracellular domain. The soluble forms of these cytokines are released by proteolytic cleavage. BTC, a heparin binding protein, was originally isolated from the conditioned media of mouse pancreatic beta tumor cells as a 32 kDa glycoprotein composed of 80 amino acid residues. The cDNA encoding human BTC was cloned from a human breast adenocarcinoma cell line (MCF7) cDNA library. Human and mouse cDNAs encode BTC precursor proteins of 178 and 177 amino acid residues, respectively. At the amino acid sequence level, human BTC precursor protein exhibits 79% identity with that of the mouse BTC precursor. In a mouse cell line transfected with human BTC cDNA, three forms of soluble human BTC have been detected: the glycosylated, intact BTC composed of 80 amino acid residues, a truncated molecule lacking 12 amino acid residues from the amino terminus, and a second truncated molecule lacking 30 amino acid residues from the amino terminus. The biological activities of these BTC forms were shown to be identical. BTC can bind to the EGF receptor and is a potent mitogen for Balb/c 3T3 fibroblasts, retinal pigment epithelial cells and vascular smooth muscle cells. |
Anti-Human Betacellulin Antibody |
|
102-P222 |
ReliaTech |
100 µg |
EUR 245.7 |
|
Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. |
 anti- Betacellulin antibody |
|
FNab00883 |
FN Test |
100µg |
EUR 606.3 |
|
|
|
Description: Antibody raised against Betacellulin |
 Human Betacellulin CLIA Kit |
|
MBS8425178-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
 Recombinant Human Betacellulin |
|
7-00223 |
CHI Scientific |
5µg |
Ask for price |
Recombinant Human Betacellulin |
|
7-00224 |
CHI Scientific |
20µg |
Ask for price |
Recombinant Human Betacellulin |
|
7-00225 |
CHI Scientific |
1mg |
Ask for price |
) Human Betacellulin (Recombinant) |
|
22060316-1 |
Glycomatrix |
5 µg |
EUR 146.42 |
Recombinant Human Betacellulin |
|
AP60110 |
SAB |
100ug |
EUR 896 |
|
|
 Recombinant Human BetaCellulin |
|
HEOPP-0212 |
Cyagen |
5ug |
Ask for price |
Recombinant Human Betacellulin |
|
cyt-330-1mg |
ProSpec Tany |
1mg |
EUR 2700 |
Recombinant Human Betacellulin |
|
cyt-330-20g |
ProSpec Tany |
20µg |
EUR 145 |
Recombinant Human Betacellulin |
|
cyt-330-5g |
ProSpec Tany |
5µg |
EUR 60 |
Recombinant Human Betacellulin |
|
MBS142207-0005mg |
MyBiosource |
0.005mg |
EUR 240 |
Recombinant Human Betacellulin |
|
MBS142207-002mg |
MyBiosource |
0.02mg |
EUR 310 |
Recombinant Human Betacellulin |
|
MBS142207-1mg |
MyBiosource |
1mg |
EUR 2880 |
Recombinant Human Betacellulin |
|
MBS142207-5x1mg |
MyBiosource |
5x1mg |
EUR 12630 |
Recombinant Human Betacellulin |
|
P1308-.005 |
ApexBio |
5ug |
EUR 108.8 |
|
Description: Peptides & Proteins|Recombinant Proteins |
Recombinant Human Betacellulin |
|
P1308-.1 |
ApexBio |
100ug |
EUR 900 |
|
Description: Peptides & Proteins|Recombinant Proteins |
Recombinant Human Betacellulin |
|
P1308-.5 |
ApexBio |
500ug |
EUR 2021.6 |
|
Description: Peptides & Proteins|Recombinant Proteins |
 Human Betacellulin ELISA KIT |
|
E42EH-268 |
EnoGene |
96T/48T |
Ask for price |
 Human Betacellulin ELISA Kit |
|
MBS009811-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Human Betacellulin ELISA Kit |
|
MBS009811-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Human Betacellulin ELISA Kit |
|
MBS009811-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Human Betacellulin ELISA Kit |
|
MBS009811-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Human Betacellulin ELISA Kit |
|
IHUBTCKT |
Innovative research |
each |
EUR 702 |
|
|
|
Description: Human Betacellulin ELISA Kit |
Human Betacellulin ELISA Kit |
|
GWB-SKR006 |
GenWay Biotech |
96 Tests |
Ask for price |
 Human betacellulin ELISA Kit |
|
MBS727932-48StripWellsCompetitive |
MyBiosource |
48-Strip-Wells-(Competitive) |
EUR 485 |
Human betacellulin ELISA Kit |
|
MBS727932-48StripWellsSandwich |
MyBiosource |
48-Strip-Wells-(Sandwich) |
EUR 485 |
Human betacellulin ELISA Kit |
|
MBS727932-5x96StripWellsCompetitive |
MyBiosource |
5x96-Strip-Wells-(Competitive) |
EUR 3020 |
Human betacellulin ELISA Kit |
|
MBS727932-96StripWellsCompetitive |
MyBiosource |
96-Strip-Wells-(Competitive) |
EUR 690 |
Human betacellulin ELISA Kit |
|
MBS727932-96StripWellsSandwich |
MyBiosource |
96-Strip-Wells-(Sandwich) |
EUR 690 |
Human Betacellulin ELISA Kit |
|
MBS763506-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3900 |
Human Betacellulin ELISA Kit |
|
MBS763506-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 340 |
Human Betacellulin ELISA Kit |
|
MBS763506-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2045 |
Human Betacellulin ELISA Kit |
|
MBS763506-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 455 |
Human Betacellulin ELISA Kit |
|
MBS824733-5x96Tests |
MyBiosource |
5x96Tests |
EUR 2880 |
Human Betacellulin ELISA Kit |
|
MBS824733-96Tests |
MyBiosource |
96Tests |
EUR 645 |
Human Betacellulin ELISA Kit |
|
MBS138113-1Kit |
MyBiosource |
1Kit |
EUR 755 |
Human Betacellulin ELISA Kit |
|
MBS138113-5x1Kit |
MyBiosource |
5x1Kit |
EUR 3455 |
 Betacellulin Human Recombinant |
|
rAP-0363 |
Angio Proteomie |
Inquiry |
Ask for price |
 Betacellulin, Recombinant, Human |
|
MBS650210-0005mg |
MyBiosource |
0.005mg |
EUR 340 |
Betacellulin, Recombinant, Human |
|
MBS650210-002mg |
MyBiosource |
0.02mg |
EUR 490 |
Betacellulin, Recombinant, Human |
|
MBS650210-5x002mg |
MyBiosource |
5x0.02mg |
EUR 2055 |
 Protein) Human Betacellulin (bTC) Protein |
|
20-abx065524 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Human Betacellulin (bTC) Protein |
|
abx065524-100g |
Abbexa |
100 µg |
EUR 537.5 |
Human Betacellulin (bTC) Protein |
|
abx065524-10g |
Abbexa |
10 µg |
EUR 212.5 |
Human Betacellulin (bTC) Protein |
|
abx065524-50g |
Abbexa |
50 µg |
EUR 375 |
 Human Betacellulin GENLISA ELISA |
|
KB1015 |
Krishgen |
1 x 96 wells |
EUR 198 |
 CLIA Kit) Human Betacellulin (bTC) CLIA Kit |
|
abx196482-96tests |
Abbexa |
96 tests |
EUR 990 |
|
|
 CLIA Kit) Human Betacellulin (BTC) CLIA Kit |
|
20-abx491043 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
|
Human Betacellulin (bTC) CLIA Kit |
|
abx196482-100l |
Abbexa |
100 µl |
Ask for price |
Human Betacellulin (bTC) CLIA Kit |
|
abx196482-50l |
Abbexa |
50 µl |
EUR 618.75 |
 ELISA Kit) Human Betacellulin (BTC) ELISA Kit |
|
abx250182-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
|
Human Betacellulin (BTC) ELISA Kit |
|
abx570040-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
|
 ELISA Kit) Human Betacellulin (bTC) ELISA Kit |
|
DLR-bTC-Hu |
DL Develop |
96T |
EUR 422 |
|
|
|
Description: serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
|
DLR-bTC-Hu-48T |
DL Develop |
48T |
EUR 574.8 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
|
DLR-bTC-Hu-96T |
DL Develop |
96T |
EUR 745.2 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Betacellulin (bTC) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
|
DL-bTC-Hu |
DL Develop |
96T |
EUR 402 |
|
|
|
Description: serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
 Human Betacellulin, BTC ELISA Kit |
|
DEIA089 |
Creative Diagnostics |
10 plates |
EUR 3126 |
|
Description: This assay is a sandwich Enzyme Linked-Immuno-Sorbent Assay (ELISA). It is developed for quantitative measurement of human BTC in serum, plasma and other biological fluids. |
 Human Betacellulin/BTC ELISA kit |
|
E22-HC017.48 |
EnoGene |
48T |
EUR 295 |
Human Betacellulin/BTC ELISA kit |
|
E22-HC017.96 |
EnoGene |
96T |
EUR 395 |
Human Betacellulin (bTC) ELISA Kit |
|
EK12923 |
SAB |
96Т |
EUR 768 |
|
|
 Human Betacellulin/BTC ELISA Kit |
|
EK5454 |
SAB |
96 tests |
EUR 599 |
|
|
Human Betacellulin (bTC) ELISA Kit |
|
SEA112Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5128.02 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
|
SEA112Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 527.48 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
|
SEA112Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 702.12 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
|
SEA112Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2799.54 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Betacellulin (bTC) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
|
4-SEA112Hu |
Cloud-Clone |
-
Ask for price
-
Ask for price
-
Ask for price
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Betacellulin (bTC) in samples from Serum, plasma, tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species. |
 Human Betacellulin/BTC ELISA Kit |
|
LF-EK50996 |
Abfrontier |
1×96T |
EUR 777.6 |
Human Betacellulin (bTC) ELISA Kit |
|
RD-bTC-Hu-48T |
Reddot Biotech |
48T |
EUR 411.8 |
|
|
|
Description: serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
|
RD-bTC-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 573.6 |
Human Betacellulin (bTC) ELISA Kit |
|
RD-bTC-Hu-96T |
Reddot Biotech |
96T |
EUR 588.3 |
|
|
|
Description: serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
|
RD-bTC-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 794.4 |
Human Betacellulin (bTC) ELISA Kit |
|
RDR-bTC-Hu-48T |
Reddot Biotech |
48T |
EUR 432.39 |
|
|
|
Description: serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
|
RDR-bTC-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 600 |
Human Betacellulin (bTC) ELISA Kit |
|
RDR-bTC-Hu-96T |
Reddot Biotech |
96T |
EUR 617.72 |
|
|
|
Description: serum, plasma, tissue homogenates, cell lysates and other biological fluids. |
Human Betacellulin (bTC) ELISA Kit |
|
RDR-bTC-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 830.4 |
Human Betacellulin/BTC ELISA Kit |
|
MBS8579158-48Tests |
MyBiosource |
48Tests |
EUR 390 |
Human Betacellulin/BTC ELISA Kit |
|
MBS8579158-5x96Tests |
MyBiosource |
5x96Tests |
EUR 2275 |
Human Betacellulin/BTC ELISA Kit |
|
MBS8579158-96Tests |
MyBiosource |
96Tests |
EUR 495 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS2020247-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 4910 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS2020247-24StripWells |
MyBiosource |
24-Strip-Wells |
EUR 340 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS2020247-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 500 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS2020247-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2675 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS2020247-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 665 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS452002-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 4700 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS452002-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 410 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS452002-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2410 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS452002-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 545 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS2701248-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 2830 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS2701248-24StripWells |
MyBiosource |
24-Strip-Wells |
EUR 240 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS2701248-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 315 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS2701248-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1480 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS2701248-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 385 |
Human Betacellulin (BTC) ELISA Kit |
|
MBS2610656-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3040 |
Human Betacellulin (BTC) ELISA Kit |
|
MBS2610656-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 285 |
Human Betacellulin (BTC) ELISA Kit |
|
MBS2610656-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1670 |
Human Betacellulin (BTC) ELISA Kit |
|
MBS2610656-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 405 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS457991-10x96Tests |
MyBiosource |
10x96Tests |
EUR 4890 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS457991-48Tests |
MyBiosource |
48Tests |
EUR 425 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS457991-5x96Tests |
MyBiosource |
5x96Tests |
EUR 2495 |
Human Betacellulin (bTC) ELISA Kit |
|
MBS457991-96Tests |
MyBiosource |
96Tests |
EUR 560 |
 ELISA Kit) Human Betacellulin(BTC) ELISA Kit |
|
EIA07641h |
Enlibio |
each |
EUR 430 |
 Recombinant Human Betacellulin, HEK |
|
cyt-1188-10g |
ProSpec Tany |
10µg |
EUR 145 |
Recombinant Human Betacellulin, HEK |
|
cyt-1188-1mg |
ProSpec Tany |
1mg |
EUR 5200 |
Recombinant Human Betacellulin, HEK |
|
cyt-1188-2g |
ProSpec Tany |
2µg |
EUR 60 |
Recombinant Human Betacellulin, HEK |
|
MBS147328-0002mg |
MyBiosource |
0.002mg |
EUR 240 |
Recombinant Human Betacellulin, HEK |
|
MBS147328-001mg |
MyBiosource |
0.01mg |
EUR 310 |
Recombinant Human Betacellulin, HEK |
|
MBS147328-1mg |
MyBiosource |
1mg |
EUR 5345 |
Recombinant Human Betacellulin, HEK |
|
MBS147328-5x1mg |
MyBiosource |
5x1mg |
EUR 23725 |
 Anti-BTC/Betacellulin Antibody |
|
MBS2400715-005mg |
MyBiosource |
0.05mg |
EUR 595 |
Anti-BTC/Betacellulin Antibody |
|
MBS2400715-5x005mg |
MyBiosource |
5x0.05mg |
EUR 2500 |
 Human BTC -Betacellulin- CLIA Kit |
|
E-CL-H0444-24Tests |
Elabscience Biotech |
24 Tests |
EUR 180 |
|
|
|
Description: Sandwich |
Human BTC -Betacellulin- CLIA Kit |
|
E-CL-H0444-48Tests |
Elabscience Biotech |
48 Tests |
EUR 546 |
|
|
|
Description: Sandwich |
Human BTC -Betacellulin- CLIA Kit |
|
E-CL-H0444-96Tests |
Elabscience Biotech |
96 Tests |
EUR 682 |
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|
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Description: Sandwich |
Human BTC -Betacellulin- CLIA Kit |
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E-CL-H0444-96Tests10 |
Elabscience Biotech |
96 Tests *10 |
EUR 6820 |
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Description: Sandwich |
Human BTC -Betacellulin- CLIA Kit |
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E-CL-H0444-96Tests5 |
Elabscience Biotech |
96 Tests *5 |
EUR 3410 |
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Description: Sandwich |
 CLIA Kit) Human bTC (Betacellulin) CLIA Kit |
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MBS2531178-5x96Tests |
MyBiosource |
5x96Tests |
EUR 2565 |
Human bTC (Betacellulin) CLIA Kit |
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MBS2531178-96Tests |
MyBiosource |
96Tests |
EUR 560 |
 Human Betacellulin Protein, Fc Tag |
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BEN-H525x |
ACROBIOSYSTEMS |
1mg |
EUR 374.5 |
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Description: Human Betacellulin, Fc Tag (BEN-H525x) is expressed from human 293 cells (HEK293). It contains AA Asp 32 - Tyr 111 (Accession # AAH11618). |
 ELISA Kit) Human BTC(Betacellulin) ELISA Kit |
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EH0044 |
FN Test |
96T |
EUR 628.92 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
 ELISA Kit) Human bTC(Betacellulin) ELISA Kit |
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ELK1403-48T |
ELK Biotech |
48T |
Ask for price |
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Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human bTC. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human bTC. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human bTC, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human bTC in the samples is then determined by comparing the OD of the samples to the standard curve. |
Human bTC(Betacellulin) ELISA Kit |
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ELK1403-96T |
ELK Biotech |
96T |
Ask for price |
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Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human bTC. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human bTC. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human bTC, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human bTC in the samples is then determined by comparing the OD of the samples to the standard curve. |
Human BTC(Betacellulin) ELISA Kit |
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RE2928H-48wells |
Reed Biotech |
48 wells |
EUR 116.55 |
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Human BTC(Betacellulin) ELISA Kit |
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RE2928H-96wells |
Reed Biotech |
96 wells |
EUR 161.55 |
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 ELISA Kit) Human bTC (Betacellulin) ELISA Kit |
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MBS8800404-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3130 |
Human bTC (Betacellulin) ELISA Kit |
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MBS8800404-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 350 |
Human bTC (Betacellulin) ELISA Kit |
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MBS8800404-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1710 |
Human bTC (Betacellulin) ELISA Kit |
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MBS8800404-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 445 |
Human bTC (Betacellulin) ELISA Kit |
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MBS2505147-10x96Tests |
MyBiosource |
10x96Tests |
EUR 4060 |
Human bTC (Betacellulin) ELISA Kit |
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MBS2505147-24Tests |
MyBiosource |
24Tests |
EUR 265 |
Human bTC (Betacellulin) ELISA Kit |
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MBS2505147-48Tests |
MyBiosource |
48Tests |
EUR 450 |
Human bTC (Betacellulin) ELISA Kit |
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MBS2505147-5x96Tests |
MyBiosource |
5x96Tests |
EUR 2265 |
Human bTC (Betacellulin) ELISA Kit |
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MBS2505147-96Tests |
MyBiosource |
96Tests |
EUR 535 |
Human BTC(Betacellulin) ELISA Kit |
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RE2928H-48wellsplate |
Reed Biotech |
48 wells plate |
EUR 126 |
Human BTC(Betacellulin) ELISA Kit |
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RE2928H-96wellsplate |
Reed Biotech |
96 wells plate |
EUR 180 |
 Anti-Mouse Betacellulin Antibody |
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103-M308 |
ReliaTech |
100 µg |
EUR 399 |
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Description: Betacellulin (BTC) is a new member of the EGF family of cytokines that is comprised of at least ten proteins including EGF, TGFα, amphiregulin, HB-EGF, and the various heregulins. All of these cytokines are synthesized as transmembrane precursors and are characterized by the presence of one or more EGF structural units in their extracellular domain. The soluble forms of these cytokines are released by proteolytic cleavage. BTC, a heparin binding protein, was originally isolated from the conditioned media of mouse pancreatic beta tumor cells as a 32 kDa glycoprotein composed of 80 amino acid residues. The cDNA encoding human BTC was cloned from a human breast adenocarcinoma cell line (MCF7) cDNA library. Human and mouse cDNAs encode BTC precursor proteins of 178 and 177 amino acid residues, respectively. At the amino acid sequence level, human BTC precursor protein exhibits 79% identity with that of the mouse BTC precursor. In a mouse cell line transfected with human BTC cDNA, three forms of soluble human BTC have been detected: the glycosylated, intact BTC composed of 80 amino acid residues, a truncated molecule lacking 12 amino acid residues from the amino terminus, and a second truncated molecule lacking 30 amino acid residues from the amino-terminus. The biological activities of these BTC forms were shown to be identical. BTC can bind to the EGF receptor and is a potent mitogen for Balb/c 3T3 fibroblasts, retinal pigment epithelial cells and vascular smooth muscle cells. |
 Human Betacellulin Recombinant Protein |
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100-332 |
ReliaTech |
20 µg |
EUR 196.35 |
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Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. |
Human Betacellulin Recombinant Protein |
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100-332S |
ReliaTech |
5 µg |
EUR 92.4 |
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Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. |
 Recombinant Human Betacellulin Protein |
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PROTP35070-2 |
BosterBio |
20ug |
EUR 380.4 |
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Description: Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein. |
 Recombinant Human Betacellulin protein |
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CD02256-5ug |
Jiaxing Korain Biotech Ltd (BT Labs) |
5ug |
EUR 176 |
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Description: Betacellulin (BTC) is a member of the EGF family of cytokines that also includes EGF, TGF-a, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. It is expressed in most tissues including kidney, uterus, liver and pancreas. BTC also presents in body fluids, including serum, milk, and colostrum. At the amino acid sequence level, human mature BTC protein exhibits 80 % identity with mouse BTC protein. The protein binds to EGFR, ERBB4 and other EGF receptor family members and acts as a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. |
 Polyclonal Antibody (Human)) Betacellulin (bTC) Polyclonal Antibody (Human) |
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4-PAA112Hu01 |
Cloud-Clone |
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- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC) |
 LumiAb ELISA Kit) Betacellulin (Human) LumiAb ELISA Kit |
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MBS9510760-1x96Wells |
MyBiosource |
1x96Wells |
EUR 520 |
Betacellulin (Human) LumiAb ELISA Kit |
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MBS9510760-5x96Wells |
MyBiosource |
5x96Wells |
EUR 2395 |
， Human) Betacellulin (HEK293-expressed)， Human |
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HY-P7328 |
MedChemExpress |
10ug |
EUR 280.8 |
 Protein (Active)) Human Betacellulin (bTC) Protein (Active) |
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20-abx655563 |
Abbexa |
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Ask for price
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Ask for price
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- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
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Human Betacellulin (bTC) Protein (Active) |
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abx655563-50g |
Abbexa |
50 µg |
EUR 3712.5 |
 Recombinant Human Betacellulin, His Tag |
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cyt-077-10g |
ProSpec Tany |
10µg |
EUR 145 |
Recombinant Human Betacellulin, His Tag |
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cyt-077-1mg |
ProSpec Tany |
1mg |
EUR 5200 |
Recombinant Human Betacellulin, His Tag |
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cyt-077-2g |
ProSpec Tany |
2µg |
EUR 60 |
Recombinant Human Betacellulin, His Tag |
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MBS144451-0002mg |
MyBiosource |
0.002mg |
EUR 240 |
Recombinant Human Betacellulin, His Tag |
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MBS144451-001mg |
MyBiosource |
0.01mg |
EUR 310 |
Recombinant Human Betacellulin, His Tag |
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MBS144451-1mg |
MyBiosource |
1mg |
EUR 5345 |
Recombinant Human Betacellulin, His Tag |
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MBS144451-5x1mg |
MyBiosource |
5x1mg |
EUR 23725 |
) CLIA kit for Human BTC (Betacellulin) |
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E-CL-H0444 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 700.8 |
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Description: A sandwich CLIA kit for quantitative measurement of Human BTC (Betacellulin) in samples from Serum, Plasma, Cell supernatant |
 Betacellulin antibody |
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70R-BR013 |
Fitzgerald |
50 ug |
EUR 312 |
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Description: Affinity purified Rabbit polyclonal Betacellulin antibody |
Betacellulin antibody |
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MBS535912-005mg |
MyBiosource |
0.05mg |
EUR 465 |
Betacellulin antibody |
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MBS535912-5x005mg |
MyBiosource |
5x0.05mg |
EUR 1945 |
 Sandwich ELISA Kit) Betacellulin (Human) Sandwich ELISA Kit |
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OK-0105 |
Assay Biotech |
1Kit |
EUR 217 |
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Description: Betacellulin (Human) Colorimetric Sandwich ELISA Kit |
 OmniKine ELISA Kit) Betacellulin (Human) OmniKine ELISA Kit |
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MBS9501832-1x96Wells |
MyBiosource |
1x96Wells |
EUR 500 |
Betacellulin (Human) OmniKine ELISA Kit |
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MBS9501832-5x96Wells |
MyBiosource |
5x96Wells |
EUR 2300 |
) ELISA kit for Human BTC (Betacellulin) |
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E-EL-H0570 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 640.8 |
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Description: A sandwich ELISA kit for quantitative measurement of Human BTC (Betacellulin) in samples from Serum, Plasma, Cell supernatant |
) ELISA kit for Human bTC (Betacellulin) |
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ELK1403 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
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Description: A sandwich ELISA kit for detection of Betacellulin from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
 Betacellulin Human Recombinant, His Tag |
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rAP-0361 |
Angio Proteomie |
Inquiry |
Ask for price |
) Sheep Polyclonal anti-human Betacellulin (BTC) |
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hAP-5047 |
Angio Proteomie |
50ug |
EUR 400 |
) Sheep Polyclonal anti-Human Betacellulin (BTC) |
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hAP-5649 |
Angio Proteomie |
50ug |
EUR 400 |
 Polyclonal Antibody (Human), PE) Betacellulin (bTC) Polyclonal Antibody (Human), PE |
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4-PAA112Hu01-PE |
Cloud-Clone |
-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with PE. |
) Betacellulin (BTC) |
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THP-0274 |
Creative BioMart |
1 vial |
EUR 3198.4 |
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Description: Protein |
 Polyclonal Antibody (Human), APC) Betacellulin (bTC) Polyclonal Antibody (Human), APC |
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4-PAA112Hu01-APC |
Cloud-Clone |
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with APC. |
 Polyclonal Antibody (Human), Cy3) Betacellulin (bTC) Polyclonal Antibody (Human), Cy3 |
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4-PAA112Hu01-Cy3 |
Cloud-Clone |
-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with Cy3. |
 Polyclonal Antibody (Human), HRP) Betacellulin (bTC) Polyclonal Antibody (Human), HRP |
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4-PAA112Hu01-HRP |
Cloud-Clone |
-
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-
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-
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-
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-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with HRP. |
 Recombinant Human Betacellulin/BTC Protein |
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RP01700 |
Abclonal |
10μg |
EUR 162.5 |
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 Recombinant human Betacellulin/BTC Protein |
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MBS201329-001mg |
MyBiosource |
0.01mg |
EUR 255 |
Recombinant human Betacellulin/BTC Protein |
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MBS201329-002mg |
MyBiosource |
0.02mg |
EUR 345 |
Recombinant human Betacellulin/BTC Protein |
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MBS201329-005mg |
MyBiosource |
0.05mg |
EUR 415 |
Recombinant human Betacellulin/BTC Protein |
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MBS201329-01mg |
MyBiosource |
0.1mg |
EUR 610 |
Recombinant human Betacellulin/BTC Protein |
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MBS201329-025mg |
MyBiosource |
0.25mg |
EUR 985 |
 Human Betacellulin/BTC PicoKine ELISA Kit |
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EK0980 |
BosterBio |
96 wells |
EUR 510 |
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Description: For quantitative detection of human Betacellulin in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
Human Betacellulin/BTC PicoKine ELISA Kit |
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MBS177180-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2755 |
Human Betacellulin/BTC PicoKine ELISA Kit |
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MBS177180-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 600 |
 Polyclonal Antibody (Human), FITC) Betacellulin (bTC) Polyclonal Antibody (Human), FITC |
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4-PAA112Hu01-FITC |
Cloud-Clone |
-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
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Description: A Rabbit polyclonal antibody against Human Betacellulin (bTC). This antibody is labeled with FITC. |
 Mouse Betacellulin |
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MBS691628-0005mg |
MyBiosource |
0.005mg |
EUR 300 |
Mouse Betacellulin |
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MBS691628-002mg |
MyBiosource |
0.02mg |
EUR 450 |
Mouse Betacellulin |
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MBS691628-5x002mg |
MyBiosource |
5x0.02mg |
EUR 1725 |
Additional, elevated osteogenic differentiation assay outcomes (Alkaline Phosphatase assay and Complete calcium content material) revealed the function of β-TCP in composite scaffolds. Altogether, outcomes counsel the potentiality of ready porous freeze dried composite scaffolds in bone tissue engineering functions.
